Abbasali Zeraati; Shahram Amini; Mohammad Samadi; Hasan Mortazi; Tina Zeraati; katayoun samadi
Volume 23, Issue 9 , 2021
Abstract
Introduction: Patients undergoing on-pump cardiac surgery are at risk of postoperative acute kidney injury (AKI). This is mainly due to some ischemic events and also pre-and postoperative stress responses which can result in postoperative organ dysfunction. Selenium (Se) as an antioxidant may help reduce ...
Read More
Introduction: Patients undergoing on-pump cardiac surgery are at risk of postoperative acute kidney injury (AKI). This is mainly due to some ischemic events and also pre-and postoperative stress responses which can result in postoperative organ dysfunction. Selenium (Se) as an antioxidant may help reduce inflammation and subsequent related complications. This study aimed to test if administration of oral Se complement before and after the on-pump cardiac surgery can reduce the incidence or severity of AKI following the operation.
Methods: In this randomized double-blind trial, the patients who were a candidate for on-pump cardiac surgery were randomly divided into two groups of intervention and control who received Se (n=60) or nothing (n=60), respectively. In the Se group, 500 µg of Se was administrated orally 14 and 2 h before surgery and every 12 h postoperatively for 2 days (overall 3000 µg), while the control group only received the routine and standard care. The patients were closely observed for the incidence and severity of postoperative AKI, using both Risk/Injury/Failure/Loss/End-stage (RIFLE) and the Acute Kidney Injury Network (AKIN) criteria.
Results: The study sample included 46 (38.3%) males and 74 (61.7%) females with a mean±SD age of 52.8±16.7 years. Both groups were similar in terms of demographic characteristics, comorbidities, and Euro-SCORE. According to the RIFLE criteria, AKI occurred in 11 (17.9%) and 13 (21.4%) patients in the Se and control group, respectively. However, based on AKIN criteria, there were 17 (28.6%) and 21 (35.7%) cases of AKI in the Se and the control group, respectively (P=0.73). The most frequent stage of AKI among patients was the first stage in both groups and the highest rate of AKI was observed within 3-4 days after the surgery in both groups.
Conclusion: The obtained results did not approve the effect of Se in AKI prevention in coronary artery bypass grafting patients.
Hossein Shahdosti; Seyed Reza Mazlom; Saeed Vaghee; Shahram Amini
Volume 22, Issue 7 , 2020
Abstract
Abstract
Background: Anxiety and depression are among the most important and common problems in patients admitted to the intensive care unit open-heart (ICU-OH). While the family plays a vital supportive role in decreasing these complications, patients are deprived of this supportive source ...
Read More
Abstract
Background: Anxiety and depression are among the most important and common problems in patients admitted to the intensive care unit open-heart (ICU-OH). While the family plays a vital supportive role in decreasing these complications, patients are deprived of this supportive source during the important post-operative days due to visiting restrictions at these wards.
Objectives: Therefore, this study aimed to evaluate the role of online video visitations on the anxiety and depression of patients at ICU-OH.
Methods: This randomized clinical trial was carried out among 66 patients at ICU-OH of Imam Reza Hospital in Mashhad, Iran. The subjects were selected by the convenience sampling method and were randomly allocated to the intervention and control groups. Data were collected using a demographic characteristics checklist and HADS. In the intervention group, online video visitations with the family were carried out three times in the morning, evening and night on the second and third days of hospitalization in ICU-OH. In the control group, patients received the routine care of the ward and had no visitations with their families. Data were collected before the surgery, as well as 24 and 48 hours after admission to the ICU-OH. In addition, data analysis was performed in
SPSS using independent t-test, Mann-Whitney U test, paired t-test, and Chi-square test.
Results: No significant difference was observed between the intervention (7.8 ± 2.2) and control (8.3 ± 2.3) groups regarding the
mean anxiety score 24 hours after the intervention (P = 0.416). However, the mean anxiety scores 48 hours after the intervention were 6.1 ± 2.3 and 7.7 ± 2.6 in the intervention and control groups, respectively, showing a significant decrease in the intervention group, compared to the control group (P = 0.010). However, the mean depression scores 24 and 48 hours after the intervention were estimated at 8.0 ± 2.0 and 7.1 ± 2.0, respectively, demonstrating no significant difference from the control group (P = 0.933 and P =0.269).
Conclusions: According to the study results, online video visitations decreased anxiety in patients at ICU-OH. Therefore, it is recom- mended that this method be used as an alternative to in-person meetings of patients at this ward.
